The American College of Surgeons 2012 Annual Clinical Congress, scheduled for September 30–October 4, 2012, at McCormick Place in Chicago, IL. The Congress will initiate the celebration of the 100 year anniversary of the founding of the American College of Surgeons. In 2012, as at the time of our founding, the Congress will promote high quality educational programs designed to educate surgeons and directly improve the health and safety of surgical patients. This year’s theme as Stewardship of Our Profession. In addition to other valuable educational efforts, various activities focusing on our profession will be highlighted. Among those are diverse Panel Sessions presented by experts from across the surgical specialties and nonsurgical disciplines, and Named Lectures delivered by top leaders in their fields. The Didactic and Skills-Oriented Postgraduate Courses will focus on important domains and will help attendees advance their knowledge and acquire new skills.